LUCAS Center for Imaging

LUCAS Center for Imaging

Department of Radiology
Lucas Center logo

LUCAS Center for Imaging

Department of Radiology

Scanners

LUCAS Center for Imaging

The LUCAS Center for Imaging houses resources devoted to research in magnetic resonance imaging (MRI) and spectroscopy (MRS). Researchers in RSL and at the LUCAS Center for Imaging have pioneered MRI/MRS technology while developing new techniques that benefit patients with stroke, brain disorders, cancer, heart disease, chronic pain, genetic disorders, joint disease and diseases of the spleen and liver. The LUCAS Center for Imaging supports collaborative and original research using human subjects and intact animal models.

 

Our facilities include 3.0T whole-body MR systems, a 7.0T MR system, and a whole-body PET/MR system complete with patient/animal preparation facilities and image processing/readout workstations. 

Signa Premier

Room Location: 3T2- P173GE 3T Premier

 

Description: 

The GE SIGNA™ Premier 3T MRI is a high-field magnetic resonance imaging system known for its advanced imaging capabilities, patient comfort features, and potential for reduced exam times. It utilizes a 3.0 Tesla magnet, providing a strong magnetic field for enhanced image quality and faster scan times compared to lower field systems. 

Daily support in MR system operation and screening and safety is provided to all researchers including faculty, post-doctoral fellows, graduate students, and visiting scholars in the LUCAS Center for Imaging and Department of Radiology; researchers from other University departments such as Psychology, Psychiatry, Neurology, Neurosurgery, and Nephrology; and Service Center users from outside of the University.

 

Features: 

The software and hardware currently allows the use of 128 channels at 3T2.

Pulse sequences include EPI, spiral, SMS and DTI.

 

Configuration: 

  • Software Revision: RX27.0 (upgraded December 2017)
  • Channels: 148
  • Shimming: Passive, Active & High Order
  • Bore Diameter: 70 cm (L-R); 49 cm vertical, no table pad; cradle width 56 cm
  • Head Coil Diameter: 8ch 23.5 cm; 32 ch Nova 18.4 cm; 48ch 23.5 cm
  • Multinuclear Spectroscopy: No
  • Maximum Table Weight: 550 lbs (max 550 lbs table in lowered position)
  • Magnetic Shielding:  Active

 

Equipment: 

Capabilities supporting fMRI studies include Eprime computer, Physiologic monitoring, Eyetracker, EDA (GSR), EEG, TMS, facial camera, video projection, audio earphones, etc.

GE Signa PET/MR

Room location: 3T1- P021GE Signa

 

Description:

Daily support in MR system operation and screening and safety is provided to all researchers including faculty, post-doctoral fellows, graduate students, and visiting scholars in the LUCAS Center for Imaging and Department of Radiology; researchers from other University departments such as Psychology, Psychiatry, Neurology, Neurosurgery, and Nephrology; and Service Center users from outside of the University.

The InsightTec Focused Ultrasound system is used to treat human and animal models.

 

Features: 

The LUCAS Center for Imaging also maintains appropriate computer systems for pulse sequence programming including the GE EPIC pulse sequence programming environment, Matlab, and other statistical and analytic tools. 

High-performance computers are available for more advanced imaging reconstruction. A substantial infrastructure of software tools exists to help manipulate data between all MRI scanners an reconstruction servers on different local network, with careful support for data protection.

Magnetom Terra.X (Impulse Edition) Scanner

Room Location: 7T- PS018

 

Description:

The Magnetom Terra.X Impulse Edition is one of 4 such systems installed globally (with more to follow) that combine a Siemens 7 Tesla superconducting magnet with an advanced gradient coil delivering stronger and faster gradients than have ever been available for basic and translational research. While the system has not received FDA clearance as a clinical device, the system operates within the non-significant risk guidelines for IRB approved studies.

  • Like other Siemens 7T systems, the magnet operates at a field strength of 6.983 T. This 2nd generation magnet incorporates active shielding and a recondensing cryostat to minimize helium consumption. The improved design of the magnet delivers excellent magnetic field homogeneity and stability.
  • The gradient system delivers a maximum gradient strength of 200 mT/m and a maximum slew rate of 900 T/m-s (compared to a typical performance for a 7T system of 50 mT/m at a slew rate of 200 T/m-s), although actual performance is generally reduced to avoid peripheral nerve stimulation. The imaging field of view is limited to 26 cm. The higher strength and slew rate allow reductions in minimum echo time for several sequences and is particularly beneficial for diffusion studies, where the stronger peak gradient strength allows for stronger diffusion encoding without increasing the echo time and the resulting signal loss.
  •  The novel design of the coil provides low residual eddy currents enabling high quality spiral and echo planar imaging for a variety of applications.
  • The system will have two RF head coils with multichannel transmit (“pTx”) capabilities for 1H imaging and spectroscopy, as well as dedicated head coils for sodium and deuterium imaging. All receiver coils will support parallel imaging methods.
  • The core system software, designated XB10, provides a vast library of pulse sequences and imaging techniques.
  • The system will be integrated with the department’s Flywheel data curation system as well as PACS systems.

 

Features:

  • Conventional spin echo and gradient echo
  •  Multi-echo gradient echo
  •  Turbo spin echo
  •  Echo planar imaging
  •  Steady-state free precession
  •  Phase contrast and time of flight angiography
  •  Localized 1H spectroscopy with editing and chemical shift imaging
  •  Radial imaging
  •  Spiral imaging
  •  Deep learning-based image enhancement
  •  Simultaneous multi-slice imaging
  •  Parallel imaging with artifact reduction
  •  Compressed sensing
  •  Prospective and retrospective physiological triggering

Magnetom Cima.X Scanner

Room Location: 3T3- P165B

 

Description:

The Magnetom Cima.X system is one of a growing number of high performance  3T systems delivering enhanced gradient capabilities in a state of the art system. The Cima.X has received clearance from the US Food and Drug Administration for marketing as a clinical device, but will be used at Stanford as a research instrument for IRB approved  studies.

  • Cima.X incorporates a state of the art, actively shielded 3T magnet with a recondensing cryostat to minimize helium consumption while delivering excellent homogeneity and stability.
  • The gradient system delivers a maximum amplitude of 200 mT/m per axis at a maximum slew rate of 200 T/m-s, although actual performance is generally limited to avoid peripheral nerve stimulation, with a 50 cm field of view to support body imaging as well as brain imaging.
  • The system will come with several RF coils, including:
  •  Embedded body transmitter
  •  BioMatrix 18 body array
  •  T/R knee array
  •  64 ch head/neck array
  •  Sodium T/R head array
  • The core system software, designated XA61, provides a vast library of pulse sequences and imaging techniques.

 

Features:

  •  Conventional spin echo and gradient echo
  •  Multi-echo gradient echo
  •  Turbo spin echo
  •  Echo planar imaging
  •  Steady-state free precession
  •  Phase contrast and time of flight angiography
  •  Localized 1H spectroscopy with editing and chemical shift imaging
  •  Radial imaging
  •  Spiral imaging
  •  Deep learning-based image enhancement
  •  Simultaneous multi-slice imaging
  •  Parallel imaging with artifact reduction
  •  Compressed sensing
  •  Prospective and retrospective physiological triggering
  •  Arterial spin labeling
  •  Dynamic contrast enhanced imaging
  •  Flow quantification
  •  MR Fingerprinting
  • The system will be integrated with the department’s Flywheel data curation system as well as PACS systems.

Mock MRI Scanner

Room Location: LUCAS Center for Imaging, Basement P0208

 

Description:

The MRI Simulator includes: ~60cm bore with tapered entry and flat façade with integrated control panel (Light, Fan, In/Out), lights, fan, speakers & subwoofer, motorized patient table with drag sensing safety stop, manual table release. A flat panel monitor is attached to the head coil for easy, high-resolution viewing of motion measurements, stimuli or movies for the scan subject.

MoTrak head motion tracking system that provides linear feedback of X,Y,Z movement and rotational feedback on X,Y,Z axis (Pitch, Roll, Yaw coordinate) based on user-defined thresholds.

Scanner sounds from a variety of MRI scan sequences are available including Localizer, High Order Shim, 2D T2-weighted FSE, 3D T1-weighted FSPGR, DTI, EPI, and ‘sprlio’ (spiral in-out fMRI).

E-Prime® stimulus presentation software is available on a separate computer.

MRI studies require long periods of scanning with minimal participant movement. The procedure can be an unsettling experience for many participants causing excessive movement resulting in unusable data and lost funds. Special populations such as children, the elderly, and psychiatric participants, are often prone to claustrophobia and anxiety in the bore of a magnet, and consequently have a much higher rate of terminating the scan session before its completion. Some centers that have dealt with these populations estimate a 50%-80% failure rate. With the use of the MRI Simulator (also known as a mock scanner) this failure rate can often be reduced below 5%, minimizing data loss.

The MRI Simulator provides a realistic approximation of an actual MRI scanner to allow habituation and training of participants in an environment less daunting than a real scanner. The MRI Simulator introduces the participant to an authentic scanning environment, permitting them to gradually become accustomed to the scanning procedure and trained to minimize movements. Allowing the participant to acclimate to the scanner before the actual session helps to prepare them and encourages a calmer and more focused participant, ultimately resulting in more productive scanning sessions.